Semisynthetic glycopeptide antibiotics derived from LY264826 active against vancomycin-resistant enterococci.

Certain derivatives of the glycopeptide antibiotic LY264826 with N-alkyl-linked substitutions on the epivancosamine sugar are active against glycopeptide-resistant enterococci. Six compounds representing our most active series were evaluated for activity against antibiotic-resistant, gram-positive p...

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Bibliographic Details
Main Authors: Nicas, T I, Mullen, D L, Flokowitsch, J E, Preston, D A, Snyder, N J, Zweifel, M J, Wilkie, S C, Rodriguez, M J, Thompson, R C, Cooper, R D
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC163498/
https://ncbi.nlm.nih.gov/pubmed/8878606
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