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Synergy between amoxicillin and gentamicin in combination against a highly penicillin-resistant and -tolerant strain of Streptococcus pneumoniae in a mouse pneumonia model.

In vivo synergy with beta-lactam antibiotics and aminoglycosides has been studied only with penicillin-susceptible Streptococcus pneumoniae strains. We evaluated the interaction between amoxicillin (AMX) and gentamicin (GEN) on the basis of in vitro checkerboard and time-kill curves and of findings...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Darras-Joly, C, Bédos, J P, Sauve, C, Moine, P, Vallée, E, Carbon, C, Azoulay-Dupuis, E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163489/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2147
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