The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells

BACKGROUND: The transmembrane protein c-kit is a receptor tyrosine kinase (KIT) and KIT is expressed in solid tumors and hematological malignancies such as gastrointestinal stromal tumor (GIST), small-cell lung cancer and chronic myelogenous leukemia (CML). KIT plays a critical role in cell prolifer...

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Detalhes bibliográficos
Main Authors: Yasuda, Akira, Sawai, Hirozumi, Takahashi, Hiroki, Ochi, Nobuo, Matsuo, Yoichi, Funahashi, Hitoshi, Sato, Mikinori, Okada, Yuji, Takeyama, Hiromitsu, Manabe, Tadao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634869/
https://ncbi.nlm.nih.gov/pubmed/17044945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-46
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