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Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function
TRPM2 proteins belong to the melastatin-related transient receptor potential or TRPM subfamily and form Ca(2+)-permeable cationic channels activated by intracellular adenosine diphosphoribose (ADPR). The TRPM2 channel subunit, like all its close relatives, is structurally homologous to the well-char...
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Autores principales: | , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1634803/ https://ncbi.nlm.nih.gov/pubmed/16822940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00606.2005 |
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