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Interleukin-1 and Host Control of Pulmonary Histoplasmosis

We found that interleukin (IL)–1β levels were elevated in the lungs of mice infected with Histoplasma capsulatum. Hence, we examined the influence that IL-1β and IL-1 signaling has on host defenses against pulmonary histoplasmosis. In IL-1 receptor 1 knockout (IL-1R(−/−)) mice challenged intratrache...

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Autori principali: Deepe, George S., McGuinness, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634801/
https://ncbi.nlm.nih.gov/pubmed/16941354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/506946
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