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Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.

In a rat model of dual infection, we studied such dihydrofolate reductase (DHFR) inhibitors as PS-15 (25 mg/kg of body weight), epiroprim (100 mg/kg), and pyrimethamine (3 mg/kg) alone or in combination with various doses of dapsone (50, 25, or 5 mg/kg) for the prevention of pneumocystosis and toxop...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Brun-Pascaud, M, Chau, F, Garry, L, Jacobus, D, Derouin, F, Girard, P M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2067
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