Mutants of feline immunodeficiency virus resistant to 2',3'-dideoxy-2',3'-didehydrothymidine.

We selected mutants of feline immunodeficiency virus (FIV) that are resistant to 2',3'-dideoxy-2',3'-didehydrothymidine (d4T). Two mutants were selected in cultured cells with a stepwise increase in d4T concentration, resulting in mutants able to replicate in 100 microM d4T. These mutants were three...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Zhu, Y Q, Remington, K M, North, T W
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.1983
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