Efficacy of single-dose ceftriaxone in experimental otitis media induced by penicillin- and cephalosporin-resistant Streptococcus pneumoniae.

We used a gerbil model of otitis media to assess the efficacy of single-dose ceftriaxone against three Streptococcus pneumoniae strains highly resistant to penicillin (MICs, 4 to 8 micrograms/ml) and with various susceptibilities to ceftriaxone (MICs, 0.5, 4, and 8 micrograms/ml). Middle ear infecti...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Barry, B, Muffat-Joly, M, Bauchet, J, Faurisson, F, Gehanno, P, Pocidalo, J J, Carbon, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.1977
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