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Clarithromycin does not affect phosphorylation of zidovudine in vitro.

Zidovudine (ZDV) and clarithromycin (CLR) are often used simultaneously in the management of patients with AIDS. While pharmacokinetic studies show decreased absorption of ZDV when it is administered with CLR, it is unknown if CLR affects the intracellular metabolism of ZDV. We investigated the effe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Rana, K Z, Darnowski, J W, Strayer, A H, Dudley, M N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1945
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