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Uptake of cefepime by phagocytosing polymorphonuclear neutrophils and subsequent intracellular killing.

Studies of the uptake of beta-lactam antibiotics indicate that they do not accumulate in phagocytic cells. Uptake of beta-lactams is thought to occur through passive diffusion, and this is limited because of their acidic nature. Many studies of antibiotic uptake have utilized either resting phagocyt...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Pruul, H, McDonald, P J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1870
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