Uptake of cefepime by phagocytosing polymorphonuclear neutrophils and subsequent intracellular killing.
Studies of the uptake of beta-lactam antibiotics indicate that they do not accumulate in phagocytic cells. Uptake of beta-lactams is thought to occur through passive diffusion, and this is limited because of their acidic nature. Many studies of antibiotic uptake have utilized either resting phagocyt...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1870 |
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