Induction of theophylline clearance by rifampin and rifabutin in healthy male volunteers.

Rifampin and rifabutin induce the metabolism of many drugs, which may result in subtherapeutic concentrations and failure of therapy. However, differences between rifabutin and rifampin in potency of induction, and the specific enzymes which are altered, are not clear. This study, involving 12 adult...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Gillum, J G, Sesler, J M, Bruzzese, V L, Israel, D S, Polk, R E
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1866
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