NorA plasmid resistance to fluoroquinolones: role of copy number and norA frameshift mutations.

Staphylococcus aureus NorA protein is a transmembrane multidrug efflux pump that confers low-level resistance to hydrophilic fluoroquinolones. The norA gene promoter is active in Escherichia coli HB101. We have examined the genetic basis of norA-mediated resistance in E. coli by introducing a wild-t...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sun, L, Sreedharan, S, Plummer, K, Fisher, L M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163392/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8807059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.7.1665
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