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New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents.

A new model for the evaluation of antifungal compounds against oropharyngeal and gastrointestinal mucosal colonization by Candida albicans was developed. To simulate the immune deficiency observed in AIDS patients, mice were depleted of CD4+ T lymphocytes by the injection of either GK1.5 hybridoma c...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Flattery, A M, Abruzzo, G K, Gill, C J, Smith, J G, Bartizal, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8807048/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.7.1604
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