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A molecular trigger of lipid binding-induced opening of a helix bundle exchangeable apolipoprotein

Apolipophorin III (apoLp-III) from the sphinx moth, Manduca sexta, is a helix bundle protein that interacts reversibly with lipoproteins. Its five elongated amphipathic α-helices are organized in an antiparallel fashion, with helices 3 and 4 connected by a short 6-residue (PDVEKE) linker helix, term...

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Autors principals: Narayanaswami, Vasanthy, Wang, Jianjun, Schieve, Dean, Kay, Cyril M., Ryan, Robert O.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16338/
https://ncbi.nlm.nih.gov/pubmed/10200268
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