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50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus.

Macrolide antibiotics like erythromycin can prevent the formation of the 50S ribosomal subunit in growing bacterial cells, in addition to their inhibitory effect on translation. The significance of this novel finding has been further investigated. The 50% inhibitory doses of erythromycin for the inh...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Champney, W S, Burdine, R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163315/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8723490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.5.1301
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