Population pharmacokinetics of ceftazidime in cystic fibrosis patients analyzed by using a nonparametric algorithm and optimal sampling strategy.

Postinfusion data obtained from 17 patients with cystic fibrosis participating in two clinical trials were used to develop population models for ceftazidime pharmacokinetics during continuous infusion. Determinant (D)-optimal sampling strategy (OSS) was used to evaluate the benefits of merging four...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Vinks, A A, Mouton, J W, Touw, D J, Heijerman, H G, Danhof, M, Bakker, W
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8723446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.5.1091
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