Relationship between rifampin MICs for and rpoB mutations of Mycobacterium tuberculosis strains isolated in Japan.

We analyzed the relationship between rifampin MICs and rpoB mutations of 40 clinical isolates of Mycobacterium tuberculosis. A point mutation in either codon 516, 526, or 531 was found in 13 strains requiring MICs of > or = 64 micrograms/ml, while 21 strains requiring MICs of < or = 1 microgram/ml s...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ohno, H, Koga, H, Kohno, S, Tashiro, T, Hara, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8849230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.4.1053
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