Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis.

Clarithromycin is compared with clindamycin for single-dose prophylaxis of streptococcal endocarditis in rats. Human-like kinetics of the two antibiotics prevented endocarditis in animals challenged with both small and large amounts of bacterial inocula. Clarithromycin was marginally superior to cli...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Vermot, D, Entenza, J M, Vouillamoz, J, Glauser, M P, Moreillon, P
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.809
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