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High-efficiency gene transfer into skeletal muscle mediated by electric pulses

Gene delivery to skeletal muscle is a promising strategy for the treatment of muscle disorders and for the systemic secretion of therapeutic proteins. However, present DNA delivery technologies have to be improved with regard to both the level of expression and interindividual variability. We report...

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Autori principali: Mir, Lluis M., Bureau, Michel F., Gehl, Julie, Rangara, Ravi, Rouy, Didier, Caillaud, Jean-Michel, Delaere, Pia, Branellec, Didier, Schwartz, Bertrand, Scherman, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC16320/
https://ncbi.nlm.nih.gov/pubmed/10200250
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