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Alteration of postantibiotic effect during one dosing interval of tobramycin, simulated in an in vitro pharmacokinetic model.

The kinetics of the postantibiotic effect (PAE) during one dosing interval of tobramycin against Staphylococcus aureus and Pseudomonas aeruginosa was investigated. We determined the PAE at different time points during this dosing interval of 12 h in an in vitro pharmacokinetic model simulating human...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: den Hollander, J G, Mouton, J W, van Goor, M P, Vleggaar, F P, Verbrugh, H A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.784
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