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Pharmacokinetics of (-)-2'-3'-dideoxy-3'-thiacytidine in woodchucks.

The woodchuck (Marmota monax) has proven to be a suitable animal model for studying hepatitis B virus (HBV) infection owing to similarities in the course of infection between woodchuck hepatitis virus (WHV) in woodchucks and HBV in humans. (-)-beta-L-2',3'-Dideoxy-3'-thiacytidine (3TC; lamivudine) i...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Rajagopalan, P, Boudinot, F D, Chu, C K, Tennant, B C, Baldwin, B H, Schinazi, R F
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.642
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