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Susceptibility of melanized and nonmelanized Cryptococcus neoformans to the melanin-binding compounds trifluoperazine and chloroquine.

Cryptococcus neoformans is an opportunistic fungal pathogen which becomes heavily melanized in the presence of phenolic substrates such as L-dopa. Various drugs are known to bind to melanin with high affinity, including the antipsychotic agent trifluoperazine and the antimalarial agent chloroquine....

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Библиографические подробности
Главные авторы: Wang, Y, Casadevall, A
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC163154/
https://ncbi.nlm.nih.gov/pubmed/8851567
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