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Susceptibility of melanized and nonmelanized Cryptococcus neoformans to the melanin-binding compounds trifluoperazine and chloroquine.

Cryptococcus neoformans is an opportunistic fungal pathogen which becomes heavily melanized in the presence of phenolic substrates such as L-dopa. Various drugs are known to bind to melanin with high affinity, including the antipsychotic agent trifluoperazine and the antimalarial agent chloroquine....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Wang, Y, Casadevall, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.541
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