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Investigation of bioequivalence and tolerability of intramuscular ceftriaxone injections by using 1% lidocaine, buffered lidocaine, and sterile water diluents.

The pharmacokinetics and tolerability of 1-g doses of ceftriaxone diluted in sterile water, 1% lidocaine, or buffered lidocaine were investigated. No difference in bioequivalence was noted between the three treatments. No difference in peak creatine kinase values was seen. By use of a quantitative p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Hayward, C J, Nafziger, A N, Kohlhepp, S J, Bertino, J S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.485
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