The anti-human immunodeficiency virus agent 3'-fluorothymidine induces DNA damage and apoptosis in human lymphoblastoid cells.

Patients infected with the human immunodeficiency virus experienced severe hematopoietic toxicity after treatment with the deoxynucleoside analog 3'-fluorothymidine (FLT). Using several methods for the analysis of genome integrity, including histochemical staining of the 3' ends of DNA and both conv...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sundseth, R, Joyner, S S, Moore, J T, Dornsife, R E, Dev, I K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.331
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