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Treatment of experimental endocarditis due to Enterococcus faecalis using once-daily dosing regimen of gentamicin plus simulated profiles of ampicillin in human serum.

We compared the efficacy of ampicillin, both alone and in combination with gentamicin given once a day (q.d.) or three times a day (t.i.d.), in the treatment of experimental enterococcal endocarditis. Ampicillin was administered by using humanlike pharmacokinetics that simulated the profiles of this...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Gavaldà, J, Cardona, P J, Almirante, B, Capdevila, J A, Laguarda, M, Pou, L, Crespo, E, Pigrau, C, Pahissa, A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.173
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