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Pharmacokinetics and metabolism of genaconazole, a potent antifungal drug, in men.

The pharmacokinetics of genaconazole, a racemic triazole antifungal agent comprising 50% RR and 50% SS enantiomers, were studied in 12 healthy male volunteers after a single oral dose of 200 mg. The serum samples were analyzed for the two enantiomers by using a chiral high-pressure liquid chromatogr...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Lin, C, Kim, H, Radwanski, E, Affrime, M, Brannan, M, Cayen, M N
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787886/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.92
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