SMN, the Spinal Muscular Atrophy Protein, Forms a Pre-Import Snrnp Complex with Snurportin1 and Importin β

The survival of motor neuron (SMN) protein is mutated in patients with spinal muscular atrophy (SMA). SMN is part of a multiprotein complex required for biogenesis of the Sm class of small nuclear ribonucleoproteins (snRNPs). Following assembly of the Sm core domain, snRNPs are transported to the nu...

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Bibliographic Details
Main Authors: Narayanan, Usha, Ospina, Jason K., Frey, Mark R., Hebert, Michael D., Matera, A. Gregory
Format: Artigo
Language:Inglês
Published: 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630493/
https://ncbi.nlm.nih.gov/pubmed/12095920
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