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Activity of lipopolysaccharide-binding protein-bactericidal/permeability-increasing protein fusion peptide in an experimental model of Pseudomonas sepsis.

A chimeric protein consisting of the N-terminal domain of lipopolysaccharide-binding protein and the C-terminal domain of bactericidal/permeability-increasing protein demonstrated a dose-dependent survival benefit (P = 0.001) and reduced endotoxin levels (P < 0.01) in neutropenic rats with Pseudomon...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Opal, S M, Palardy, J E, Jhung, J W, Donsky, C, Romulo, R L, Parejo, N, Marra, M N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2813
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