Multiple-dose pharmacokinetics and distribution in tissue of terbinafine and metabolites.

The pharmacokinetics of terbinafine and its inactive metabolites SDZ 86-621 (the N-demethyl form), SDZ 280-027 (the carboxybutyl form), and SDZ 280-047 (N-demethyl- carboxybutyl form) in plasma were characterized for 10 healthy male subjects receiving 250 mg of terbinafine orally once a day for 4 we...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Kovarik, J M, Mueller, E A, Zehender, H, Denouël, J, Caplain, H, Millerioux, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2738
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