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Single- and multiple-dose pharmacokinetics of AM-1155, a new 6-fluoro-8-methoxy quinolone, in humans.

The pharmacokinetics of AM-1155, a new 6-fluoro-8-methoxy quinolone, was examined in healthy male volunteers after the oral administration of a single dose of 100, 200, 400, or 600 mg and multiple doses of 300 mg twice daily for 6.5 days (13 total doses). Throughout the whole study period, AM-1155 w...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Nakashima, M, Uematsu, T, Kosuge, K, Kusajima, H, Ooie, T, Masuda, Y, Ishida, R, Uchida, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8592993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2635
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