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Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedy.

Bioassay-guided fractionation of extracts of Toddalia asiatica, a plant used by the Pokot tribe of Kenya to treat fevers, has yielded the alkaloid nitidine as the major antimalarial component. Fractions containing nitidine have in vitro 50% inhibitory concentrations against Plasmodium falciparum in...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Gakunju, D M, Mberu, E K, Dossaji, S F, Gray, A I, Waigh, R D, Waterman, P G, Watkins, W M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8592987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2606
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