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Killing activity of cefpirome against penicillin-resistant Streptococcus pneumoniae isolates from patients with meningitis in a pharmacodynamic model simulating the cerebrospinal fluid concentration profile.

An in vitro pharmacodynamic model was used to determine the killing kinetics of cefpirome against 20 Streptococcus pneumoniae strains (penicillin G MICs, > 0.125 to 2 micrograms/ml) isolated from patients with meningitis. The concentration of cefpirome was adjusted dynamically to simulate the median...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Fitoussi, F, Doit, C, Sandin, A, Pechinot, A, Kazmierczack, A, Geslin, P, Bingen, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8585745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.11.2560
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