Methionine recycling pathways and antimalarial drug design.

5'-Deoxy-5'-(methylthio)adenosine (MTA) is an S-adenosylmethionine metabolite that is generated as a by-product of polyamine biosynthesis. In mammalian cells, MTA undergoes a phosphorolytic cleavage catalyzed by MTA phosphorylase to produce adenine and 5-deoxy-5-(methylthio)ribose-1-phosph...

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Bibliografiske detaljer
Main Authors: Sufrin, J R, Meshnick, S R, Spiess, A J, Garofalo-Hannan, J, Pan, X Q, Bacchi, C J
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162974/
https://ncbi.nlm.nih.gov/pubmed/8585735
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