Methionine recycling pathways and antimalarial drug design.

5'-Deoxy-5'-(methylthio)adenosine (MTA) is an S-adenosylmethionine metabolite that is generated as a by-product of polyamine biosynthesis. In mammalian cells, MTA undergoes a phosphorolytic cleavage catalyzed by MTA phosphorylase to produce adenine and 5-deoxy-5-(methylthio)ribose-1-phosphate (MTRP)...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sufrin, J R, Meshnick, S R, Spiess, A J, Garofalo-Hannan, J, Pan, X Q, Bacchi, C J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8585735/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.11.2511
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