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OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa.

Multidrug-resistant derivatives of Pseudomonas aeruginosa PAO1 were obtained after stepwise selection on tetracycline or erythromycin. Two phenotypes were generated. The tetracycline-resistant mutant (TETR) was phenotypically similar to OprM-overexpressing strains. This group displayed cross-resista...

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Published in:Antimicrob Agents Chemother
Main Authors: Hamzehpour, M M, Pechere, J C, Plesiat, P, Köhler, T
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8585714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.11.2392
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