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Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli.

The DNA fragment (3.3 kb) containing the erythromycin resistance determinant was cloned from Escherichia coli Tf481A and sequenced. Deletion and complementation analyses indicated that the expression of high-level resistance to erythromycin requires two genes, mphA and mrx, which encode macrolide 2'...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Noguchi, N, Emura, A, Matsuyama, H, O'Hara, K, Sasatsu, M, Kono, M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8619599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.10.2359
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