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Matrix metalloproteinases contribute to endotoxin and interleukin-1β induced vascular dysfunction

BACKGROUND AND PURPOSE: The acute vascular inflammatory dysfunction associated with endotoxaemia may reflect an imbalance between matrix metalloproteinases (MMPs) and their natural inhibitors (TIMPs), induced by the endotoxin. This possibility was tested in rat aortic tissue. EXPERIMENTAL APPROACHES...

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Main Authors: Lalu, M M, Cena, J, Chowdhury, R, Lam, A, Schulz, R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1629401/
https://ncbi.nlm.nih.gov/pubmed/16880766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706823
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