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A retinitis pigmentosa GTPase regulator (RPGR)- deficient mouse model for X-linked retinitis pigmentosa (RP3)

The X-linked RP3 locus codes for retinitis pigmentosa GTPase regulator (RPGR), a protein of unknown function with sequence homology to the guanine nucleotide exchange factor for Ran GTPase. We created an RPGR-deficient murine model by gene knockout. In the mutant mice, cone photoreceptors exhibit ec...

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Detalhes bibliográficos
Main Authors: Hong, Dong-Hyun, Pawlyk, Basil S., Shang, Jingzi, Sandberg, Michael A., Berson, Eliot L., Li, Tiansen
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16294/
https://ncbi.nlm.nih.gov/pubmed/10725384
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