Pharmacokinetics and metabolism of 14C-isepamicin in humans following intravenous administration.

Twelve healthy adult male volunteers received 1 g (base equivalent) of 14C-isepamicin (131 microCi) as an intravenous bolus over 5 min. The areas under the plasma concentration-time curves at infinity for isepamicin (196 micrograms*h/ml) and total radioactivity (164 micrograms*h/ml) were similar, in...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lin, C, Korduba, C, Affrime, M, Radwanski, E, Nomeir, A, Batra, V, Cutler, D, Cayen, M N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8619567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.10.2201
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