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Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes

Selectin-dependent cell adhesion mediates inflammatory extravasation and routine homing of lymphocytes. Most resting peripheral T lymphocytes lack expression of sialyl Lewis X, the carbohydrate ligand for selectins, and are induced to strongly express it upon activation. T helper 1 (Th1) cells are k...

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Bibliografske podrobnosti
Main Authors: Chen, Guo-Yun, Osada, Hirotaka, Santamaria-Babi, Luis F., Kannagi, Reiji
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1629005/
https://ncbi.nlm.nih.gov/pubmed/17075044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607926103
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