Cloning and characterization of a novel, plasmid-encoded trimethoprim-resistant dihydrofolate reductase from Staphylococcus haemolyticus MUR313.

In recent years resistance to the antibacterial agent trimethoprim (Tmp) has become more widespread, and several trimethoprim-resistant (Tmpr) dihydrofolate reductases (DHFRs) have been described from gram-negative bacteria. In staphylococci, only one Tmpr DHFR has been described, the type S1 DHFR,...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Dale, G E, Langen, H, Page, M G, Then, R L, Stüber, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8540692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.9.1920
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