Timing of penicillin treatment influences the course of Streptococcus pneumoniae-induced middle ear inflammation.

Penicillin treatment timing, using the chinchilla pneumococcal otitis media model, was investigated. Early treatment (when approximately 10(3) pneumococcal CFU/ml was present in middle ear fluid) significantly accelerated inflammatory-cell influx, whereas late treatment (with approximately 10(7) pne...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sato, K, Quartey, M K, Liebeler, C L, Giebink, G S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486944/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1896
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