K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine.

Cloned variants of human immunodeficiency virus type 1 that contain the K65R mutation in reverse transcriptase have previously been shown to display approximately 10- to 30-fold resistance against 2',3'-dideoxycytidine, 2',3'-dideoxyinosine, and 2',3'-dideoxy-3'-th...

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Détails bibliographiques
Auteurs principaux: Gu, Z, Salomon, H, Cherrington, J M, Mulato, A S, Chen, M S, Yarchoan, R, Foli, A, Sogocio, K M, Wainberg, M A
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC162849/
https://ncbi.nlm.nih.gov/pubmed/7486942
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