In vitro activities of PS-15, a new dihydrofolate reductase inhibitor, and its cyclic metabolite against Mycobacterium avium complex.

PS-15, a new dihydrofolate reductase inhibitor, and its cyclic metabolite were evaluated for in vitro activity against 31 clinical Mycobacterium avium complex isolates. Broth dilution MICs of PS-15 ranged from 16 to 64 micrograms/ml. The cyclic metabolite was three to five times more active than the...

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Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Meyer, S C, Majumder, S K, Cynamon, M H
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1995
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1862
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