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An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1
One feature shared by all Shaker-type voltage-gated K(+) channels is a highly conserved domain (T1) located in the cytoplasmic N terminus. The T1 domain is a key determinant of which subtypes can form heteromultimeric channels, suggesting that T1 functions during channel assembly. To better define t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16284/ https://ncbi.nlm.nih.gov/pubmed/10716722 |
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