Effect of pH on activities of novel beta-lactamases and beta-lactamase inhibitors against these beta-lactamases.

The effects of acidic conditions on activities of seven beta-lactamases--TEM-1 (class A), KOXY (class A), IMP-1 (class B), AmpC (class C), MOX-1 (class C), OXA-5 (class D), and PSE-2 (class D)--and their inhibitors were measured. The enzymatic activities of KOXY, IMP-1, and MOX-1 at pH 5.8 were slig...

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Bibliographic Details
Main Authors: Ohsuka, S, Arakawa, Y, Horii, T, Ito, H, Ohta, M
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162839/
https://ncbi.nlm.nih.gov/pubmed/7486932
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