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Inhibition of growth of Histoplasma capsulatum yeast cells in human macrophages by the iron chelator VUF 8514 and comparison of VUF 8514 with deferoxamine.

Histoplasma capsulatum requires intracellular iron to survive and multiply within human and murine macrophages (M phi). Thus, iron chelators may be useful compounds in the treatment of histoplasmosis. In the present study we compared the efficacies of five different iron chelators with deferoxamine...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Newman, S L, Gootee, L, Stroobant, V, van der Goot, H, Boelaert, J R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1824
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