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Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons

The mammalian suprachiasmatic nucleus (SCN) is a master circadian pacemaker. It is not known which SCN neurons are autonomous pacemakers or how they synchronize their daily firing rhythms to coordinate circadian behavior. Vasoactive intestinal polypeptide (VIP) and the VIP receptor VPAC(2) (encoded...

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Bibliographic Details
Main Authors: Aton, Sara J, Colwell, Christopher S, Harmar, Anthony J, Waschek, James, Herzog, Erik D
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1628303/
https://ncbi.nlm.nih.gov/pubmed/15750589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1419
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