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Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.

Spontaneous quinolone-resistant mutants obtained from Salmonella typhimurium Su694 were screened for mutations by direct DNA sequencing of an amplified PCR gyrA fragment. Substitutions Ser-83-->Phe (Ser83Phe), Ser83Tyr, Asp87Tyr, and Asp87Asn and double mutation Ala67Pro-Gly81Ser, which resulted in...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Reyna, F, Huesca, M, González, V, Fuchs, L Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1621
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