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Product of fosC, a gene from Pseudomonas syringae, mediates fosfomycin resistance by using ATP as cosubstrate.

Pseudomonas syringe PB-5123, a producer of fosfomycin, is resistant to high concentrations of the antibiotic. Two possible mechanisms of resistance have been detected: (i) impermeability to exogenous fosfomycin, even in the presence of sugar phosphate uptake inducers, and (ii) antibiotic phosphoryla...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: García, P, Arca, P, Evaristo Suárez, J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1569
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