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In vitro and in vivo antifungal activities of DU-6859a, a fluoroquinolone, in combination with amphotericin B and fluconazole against pathogenic fungi.

DU-6859a is an investigational fluoroquinolone agent with potent bactericidal activity, but by itself it has no antifungal activity. When combined with amphotericin B (AmB), however, DU-6859a clearly enhanced the in vitro antifungal activity of AmB against Candida albicans, Candida tropicalis, Candi...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Nakajima, R, Kitamura, A, Someya, K, Tanaka, M, Sato, K
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1517
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